The Yenepoya Research Centre (YRC), established in 2008, is a constituent unit of Yenepoya (Deemed to be University). YRC is devoted to multidisciplinary research spanning fundamental, applied, and translational research. YRC has state-of-the-art facilities and resources to foster cutting-edge research and innovation involving various stakeholders. The Centre adheres to the highest ethical standards, research integrity, follows Good Laboratory Practices, and holds ISO 17025:2017 compliance certification.The biomedical research at YRC is complemented with the Yenepoya Medical College Hospital with super-speciality departments and other constituent institutions, including those specialising in alternative medicine. The passionate research team with international experience under a collaborative and inclusive environment drives the achievements by adpating transformative emerging technologies. The academic programs offered by YRC lays a robust foundation for a promising R&D career in academia and industry, as evidenced by the global alumni presence. YRC plays a pivotal role in promoting entrepreneurship among students and faculties through the Yenepoya Technology Incubator. The research thrust areas align with the nation’s effort in achieving the United Nations Sustainable Development Goals, while addressing the challenging issues at regional and national priority areas.

Vision

To generate new knowledge towards national development through quality research integrated with the highest ethical standards

Mission
  • To engage in high quality research integrating both basic and translational research across multiple disciplines, driving towards therapeutics of human health

  • To cultivate critical thinking that can spark creativity and innovation among students and young researchers to make them leaders in the field of science and technology

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FACULTY

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PhD Awarded

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PATENTS

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PUBLICATIONS

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News and Updates

Achievements

Publications

  1. Krishnan S.; Kanthaje S.; Rekha P.D.; Mujeeburahiman M.; Ratnacaram C.K.. Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer. International Review of Cell and Molecular Biology. 2025; 391()
  2. Rai A.B.; Codi J.A.K.; Kotimoole C.N.; Ramesh P.; Narayana V.K.; Shaji V.; Prasad T.S.K.. Data-Independent Acquisition Analysis to Identify Serum Biomarkers and Neoantigens for Differentiating Colorectal Cancer from Inflammatory Bowel Diseases. Journal of Proteome Research. 2025; ()
  3. Hameed A.; McDonagh F.; Sengupta P.; Miliotis G.; Sivabalan S.K.M.; Szydlowski L.; Simpson A.; Singh N.K.; Rekha P.D.; Raman K.; Venkateswaran K.. Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus. Microbiology Spectrum . 2025; 13(1)
  4. Nekrakalaya B.; Kotimoole C.N.; Arefian M.; Prasad T.S.K.; Palliyath G.K.; Veerappa Hanumanthappa P.; Pandian Ramasubramania T.P.; Bangalore Jayaseelan N.K.; Muddumadiah C.; Santhappan P.; Muliyar Krishna R.. A Gel-Free Genome Annotation Provides Insights into the Proteome of the Oomycete Phytophthora meadii, a Disease-Causing Pathogen in Economically Important Crops. OMICS A Journal of Integrative Biology. 2025; ()
  5. Pavan S.R.; Prabhu A.. Black Phosphorus for Biosensing and Imaging Applications. Two-Dimensional Nanomaterials for Biosensing and Imaging Applications. 2025; ()
  6. Salam A.S.A.; Anchan R.V.; Murugan S.S.; Majhi D.; Venkatesan J.. The Potential Use of Algae-Derived Green Nanomaterials in Cancer Therapy. Nano-formulation of Dietary Phytochemicals for Cancer Management. 2025; ()
  7. Manzoor M.; Suryavanshi M.V.; Mujeeburahiman M.; Arun A.B.; Miller A.W.; Shouche Y.S.; Rekha P.D.. Urine microbiome profiles in patients with different types of kidney stones. FEMS Microbiology Letters. 2025; 372()
  8. Prashanth S.; Kadandelu M.; Raghu S.V.; Prasad K.S.; Adhikari A.V.. Conductive nano nickel oxide/hydroxide paper electrochemical sensor for serotonin detection in genetically engineered Drosophila. Journal of Materials Chemistry B. 2025; ()
  9. Dcunha R.; Aravind A.; Bhaskar S.; Mutalik S.; Mutalik S.; Kalthur S.G.; Kumar A.; Hegde P.; Adiga S.K.; Zhao Y.; Kannan N.; Prasad T.S.K.; Kalthur G.. Enhanced cell survival in prepubertal testicular tissue cryopreserved with membrane lipids and antioxidants rich cryopreservation medium. Cell and Tissue Research. 2025; 399(1)
  10. Kapoor A.; Meitei N.S.; Bisht V.S.; Najar M.A.; Giri K.; Prasad T.S.K.; Ambatipudi K.. Lactation stage-specific variations in health and lipid-associated milk fat globule membrane proteins in Holstein Friesian cow and Murrah buffalo. International Dairy Journal. 2025; 160()
  11. Bhat S.; Narayana V.K.; Prasad T.S.K.. Metabolomics studies in cushing’s syndrome: recent developments and perspectives. Expert Review of Proteomics. 2025; 22(2)
  12. Ramesh P.; Kandel Codi J.A.; Prasad T.S.K.. Proteins Biomarkers for Diagnosing Gastric Cancers: Perspectives Through Mass Spectrometry-Based Discoveries. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  13. Yukta; Sarkar O.; Mutthuraj D.; Dagamajalu S.; Basalingappa K.M.. Small Molecule Therapeutics in Breast Cancer: Current Approaches and Future Directions. Small Molecules for Cancer Treatment. 2025; ()
  14. Parate S.S.; Viayakumar M.; Prasad T.S.K.. Ex Vivo Drug Assay as a Potential Hospital-Based Testing Platform for Clinical Research and Personalized Treatment for Solid Tumors. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  15. Upadhyay S.; Shetty R.; Prasad T.S.K.. Prospects for the Discovery of Actionable Molecular Targets for Triple Negative Breast Cancer. Protein Biomarkers: Discovery and Applications in Clinical Diagnostics. 2025; ()
  16. Aravind A.; Shaji V.; Ahmed M.; Dagamajalu S.; Vijayakumar M.; Prasad T.S.K.; Raju R.. An assembled molecular signaling map of interleukin-24: a resource to decipher its multifunctional immunoregulatory role in pathophysiological conditions. Frontiers in Immunology. 2025; 16()
  17. Gopalakrishnan A.P.; Shivamurthy P.B.; Ahmed M.; Ummar S.; Ramesh P.; Thomas S.D.; Mahin A.; Nisar M.; Soman S.; Subbannayya Y.; Raju R.. Positional distribution and conservation of major phosphorylated sites in the human kinome. Frontiers in Molecular Biosciences. 2025; 12()
  18. Sreelakshmi K.; Hemavathi K.N.; Raju R.; Sameer K.V.B.; Keshava Prasad T.S.; Sudhakaran P.R.; Abhinand C.S.. Identification and stability analysis of potential ADP-ribose modification sites on vascular endothelial growth factor (VEGF) through molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics. 2025; 43(7)
  19. Suchitha G.P.; Upadhyay S.S.; Pervaje R.; Keshava Prasad T.S.; Dagamajalu S.. Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach. BioImpacts. 2025; 15()
  20. Rahmath N.A.K.; Lin S.-Y.; Young C.-C.; Hameed A.. Volatile dimethyl disulphide emission from Burkholderia cepacia LS-044 suppresses metabolism and budding in caspofungin-resistant Nakaseomyces glabratus NT2. Scientific Reports. 2025; 15(1)
  21. Suchitha G.P.; Rai A.B.; Pervaje R.; Kotimoole C.N.; Modi P.K.; Keshava Prasad T.S.; Dagamajalu S.. Proteomic analysis reveals anticancer mechanisms of Bhallataka taila in inhibiting lung cancer progression and metastasis. Molecular Omics. 2025; 21(2)
  22. Avvadukkam J.; Kodoth A.K.; Subramani T.M.; Bhandari S.G.; Kaiprath D.; Kunhanna S.B.; Venugopal D.M.; Raghu S.V.. Development of pH-Responsive Hydrogel Excipient From Karaya Gum for Improved Oral Delivery of Donepezil Hydrochloride in Alzheimer's Disease Treatment. Journal of Applied Polymer Science. 2025; 142(12)
  23. Sunitha M.S.; Naik P.; Vishnumurthy K.A.; Adhikari A.V.. Synthesis of nonlinear heteroaromatic donor–acceptor conjugated polymers: Structural, theoretical, electrochemical, and optical properties. Polymer Engineering and Science. 2025; 65(4)
  24. V S S.; De S.; Shetty S.; K D.; A R Y.; A J.; Prabhu S.; Pinto R.. Mechanistic insights into the formation of phase pure V2O5 2D nanostructures: Advanced fourier transform-raman spectroscopy analysis. Thin Solid Films. 2025; 815()
  25. Ahmed S.M.; Laha S.; Ifthikar M.A.; Das R.; Das S.P.. MCM10: A potential biomarker for cervical cancer and precancerous lesions. Gene. 2025; 936()
  26. Shastry R.P.; Hameed A.; Banerjee S.; Prabhu A.; Bajire S.K.; Pavan S.R.; Dhanyashree H.R.; Kotimoole C.N.; Stothard P.; Surya S.; Keshava Prasad T.S.; Shetty R.; Shen F.-T.; Bhandary Y.P.. Tryptic oncopeptide secreted from the gut bacterium Cronobacter malonaticus PO3 promotes colorectal cancer. Scientific Reports. 2025; 15(1)
  27. Shah S.; Paudel M.R.; Thapa B.B.; Sharma H.; Kashyap A.K.; Rekadwad B.N.; Sharma R.; Sharma J.; Pant B.. Extract from endophytic Fusarium isolates stimulates seed germination of the host and protocorm development of non-host orchids. Communicative and Integrative Biology . 2025; 18(1)
  28. Sasikumar J.; Shaikh H.A.; Naik B.; Laha S.; Das S.P.. Emergence of fungal hybrids – Potential threat to humans. Microbial Pathogenesis. 2025; 200()
  29. Biju P.; Shenoy M.M.; Tellis R.; Bhat R.; Das R.; Prabhu A.; Ahmed M.G.; Ghate V.. Novel Ketoconazole-Loaded Niosomal Gel with Carbamide for Enhanced Topical Delivery and Skin Hydration in Fungal Infections. Journal of Pharmaceutical Innovation. 2025; 20(2)
  30. Das U.; Shanavas S.; Jayaprakash M.; Senthil Kumar A.; Kushwaha R.; Mondal D.; Maity S.; Ghosh P.; Kar B.; Banerjee S.; Sudheer Shenoy P.; Bose B.; Paira P.. Reactive Oxygen Species Inducing Triazolylpyridine-Based Ru(II)/Ir(III) Complexes for Therapeutically Enhanced Triple-Negative Breast Cancer Treatment. Journal of Medicinal Chemistry. 2025; 68(3)
  31. Mallick S.; Narayana V.K.; Rai A.B.; Upadhyay S.S.; Prasad T.S.K.; P S.S.; Bose B.. Hematopoietic stem cell conditioned media induces apoptosis in colorectal cancer stem cells via dysregulation of HSP90 and 26S proteasome system. International Journal of Biochemistry and Cell Biology. 2025; 184()
  32. Farooq J.; Sultana R.; Prabhu A.; Kayarohanam S.; Gupta G.; Subramaniyan V.. Mitigation of 5-Fluorouracil-Induced Nephrotoxicity: The Protective Role of Thymoquinone and Hesperidin in vitro and in vivo. Natural Resources for Human Health. 2025; 5(2)
  33. M D.L.. Stress mediators: Cancer's double Dilemma – Navigating the error-prone path of non-homologous end joining. Medical Hypotheses. 2025; 200()
  34. Singh S.R.; Kittur B.; Bhavi S.M.; Thokchom B.; Padti A.C.; Bhat S.S.; Bajire S.K.; Shastry R.P.; Srinath B.S.; Sillanpää M.; Harini B.P.; Yarajarla R.B.. The effect of Clitoria ternatea L. flowers-derived silver nanoparticles on A549 and L-132 human cell lines and their antibacterial efficacy in Caenorhabditis elegans in vivo. Hybrid Advances. 2025; 8()
  35. Nisar M.; Soman S.P.; Sreelan S.; John L.; Pinto S.M.; Kandasamy R.K.; Subbannayya Y.; Prasad T.S.K.; Kanekar S.; Raju R.; Devasahayam Arokia Balaya R.. ProteoArk: A One-Pot Proteomics Data Analysis and Visualization Tool for Biologists. Journal of Proteome Research. 2025; 24(3)
  36. Kumara B.N.; Aziz R.A.; Sathish Kumar M.; Raghu S.V.; Sudhakara Prasad K.. Understanding photoluminescent carbon nanodots interaction with Human Corneal Epithelial cells and Drosophila melanogaster model. Biochemical and Biophysical Research Communications. 2025; 771()
  37. Rawat A.; Antil N.; Meenakshi; Deshmukh B.; Rai A.B.; Nagar A.; Kumar N.; Prasad T.S.K.; Karmodiya K.; Sharma P.. PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum. Nature Communications . 2025; 16(1)
  38. Bisht V.S.; Kumar D.; Najar M.A.; Giri K.; Kaur J.; Prasad T.S.K.; Ambatipudi K.. Drug response-based precision therapeutic selection for tamoxifen-resistant triple-positive breast cancer. Journal of Proteomics. 2025; 310()
  39. Moharana S.S.; Mallick S.; Pinto J.R.; Shenoy P S.; Bose B.. Osteo-inductive potential of homoeopathy potencies of Asafoetida on multipotent mesenchymal stem cells in vitro. 3 Biotech. 2025; 15(5)
  40. Naik B.; Sasikumar J.; Das S.P.. From Skin and Gut to the Brain: The Infectious Journey of the Human Commensal Fungus Malassezia and Its Neurological Consequences. Molecular Neurobiology. 2025; 62(1)
  41. Krishna S.; Sequeira J.J.; Mustak M.S.; Das R.. Mitochondrial DNA HVRII (Poly-C) and HVRIII (Poly-CA) tandem repeat variation in the Koraga population. Egyptian Journal of Medical Human Genetics. 2025; 26(1)
  42. Mandal S.; Mitra A.; Bose B.; Shenoy P S.. Quercetin and Kaempferol Mitigate Endotoxin-Induced Skeletal Muscle Wasting by Inhibiting KLF15 Expression and Restoring the Antioxidant System. FASEB Journal. 2025; 39(13)
  43. Ghosh D.; Aravind N.A.. Reptile Love: Are We Treating Them Humanely?. Animal Behavior in the Tropics: Vertebrates. 2025; ()
  44. Thomas M.R.; Badekila A.K.; Pai V.; Nijil S.; Bhandary Y.; Rai A.; Kini S.. Navigating Tumor Microenvironment Barriers with Nanotherapeutic Strategies for Targeting Metastasis. Advanced Healthcare Materials. 2025; 14(7)
  45. Sanjana N.S.; Maske V.B.; Devasya R.P.; Rekadwad B.N.. Draft genome sequence of an antibiotic-resistant Heyndrickxia oleronia strain UL23-01-03 isolated from the Arabian Sea coast, Dakshina Kannada, India. Microbiology Resource Announcements. 2025; 14(7)
  46. Roy O.; Ammankallu S.; Narayana V.K.; Narayana C.; Hebbar S.; Adiga P.K.; Joshi M.B.; Gowda J.; Kumar A.; Adiga S.K.; Ritting M.; Kannan N.; Prasad T.S.K.; Kalthur G.. Mass Spectrometric Analysis of Clomiphene Citrate-induced Changes in the Secretome Profile of PAX8-positive Human Fallopian Tube Secretory Epithelial Cells and Identification of Biomarkers Relevant to Reproduction and Pregnancy. Reproductive Sciences. 2025; 32(7)
  47. Narayanan V A.; Yamajala R.B.R.D.; Venkatesan J.; Pang M.-G.; Gedda G.. Emerging Carbon Dots Nanomaterials for Ovarian Cancer Diagnosis and Therapy. Current Drug Targets. 2025; ()
  48. Rai A.; Subramaniyan Y.; Fathima F.; Rekha P.D.. Broad-spectrum antimicrobial properties of linalool: supporting its pharmacological use in chronic wound infections by pathogens within the ESKAPE group and polymicrobial biofilms. World Journal of Microbiology and Biotechnology. 2025; 41(3)
  49. Pinto J.R.; Bhat K.D.; Bose B.; Shenoy P.S.. Correction to: Irisin: muscle’s novel player in endoplasmic reticulum stress and disease (Molecular and Cellular Biochemistry, (2025), 10.1007/s11010-025-05225-y). Molecular and Cellular Biochemistry. 2025; ()
  50. Suchithra K.V.; Hameed A.; Surya S.; Mahammad S.; Arun A.B.. Dual phage-incorporated electrospun polyvinyl alcohol-eudragit nanofiber matrix for rapid healing of diabetic wound infected by Pseudomonas aeruginosa and Staphylococcus aureus. Drug Delivery and Translational Research. 2025; 15(3)

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